MoA: Inhibits prostaglandin synthesis by blocking cyclooxygenase-1 and cyclooxygenase-2.
Indications: Moderate-Severe Pain
Contraindications: Asthma, Liver Impairment, Renal Impairment, Bleeding, Peptic Ulcer Disease, Anemia
Side Effects: Heartburn, Ulcers, Headache
Drug Interactions: Anticoagulants, Diuretics
Nursing Implications:
- This medication increases the risk of thrombotic events, myocardial infaraction, and stroke.
- NSAIDs are commonly taken with food, milk, or an antacid to decrease GI irritation and increase absorption.
- Risk for complications include but are not limited to Acute Renal Failure, Pulmonary Edema, Hepatotoxicity, and Ototoxicity.
- Long term use of this medication can lead to Chronic Kidney Disease, Stomach Ulcers.
