MoA: Alters DNA synthesis to induce bactericidal effects.
Indications: Gram(-) Bacteria, Urinary Tract Infection, Respiratory Infection, Musculoskeletal Infection, GI Infection, Skin Infection
Side Effects: GI Distress
Drug Interactions: Sucralfate, Antacids, Iron Salts, Dairy Products, Probenecid, Nitrofurantoin, Anticoagulants, Alcohol
Nursing Implications:
- This medication can cause ruptured tendons and tendinitis.
- Take this medication with water.
- Drugs that negatively interact with quinolones may be consumed 1hr before or 1hr after quinolone intake.
- Monitor ECG for Prolonged QT interval.
- Assess for signs of Thrush: white patches in the mouth, cheilitis, and loss of taste.
- Monitor for GI distress as Clostridium Difficile (C.diff) can occur when taking antibiotics.
- Take the full antibiotic course to decrease risk of antibiotic resistance.
