MoA: Disrupts folic acid synthesis to prevent bacterial replication. Inhibits immune and inflammatory response.
Indications: Gram(+,-) Bacteria, UTI, HIV-associated Pneumonia, Staphylococcus Infections, MRSA
Contraindications: Pregnant Women, Infants
Side Effects: Headache, GI Distress
Drug Interactions: Celebrex, Alcohol
Nursing Implications:
- Educate the patient on complications such as: Hemolytic Anemia, Aplastic Anemia, Agranulocytosis, Thrombocytopenia, Photosensitivity, Exfoliative Dermatitis, Stevens-Johnson Syndrome, and Epidermal Necrolysis.
- Take medication with water, increase daily water intake, and take this medication with food.
- Ensure the patient understands to take the full antibiotic course to decrease risk of antibiotic resistance.
